Does Prozac cause weight loss?

“I started taking Prozac a few months ago and recently noticed my appetite isn’t the same and the number on the scale has gone down. I wasn’t trying to lose weight, so now I’m wondering, does Prozac cause weight loss?”

Flávia Costa
Pharmacist

Yes, Prozac can cause weight loss in some people, mainly because it may reduce appetite and lead to eating fewer calories during the day. However, this effect is considered a side effect and not a reliable or approved method for weight loss.

Prozac increases serotonin levels in the brain, which can influence mood and appetite control. Because of this, some people notice a temporary decrease in hunger and a small reduction in body weight. The exact way this happens is not fully understood, and the response varies from person to person.

Prozac is not approved for weight loss and should not be used to treat obesity or being overweight. Medical organizations note that after about four to six months, some people regain the weight they initially lost while taking it. Its approved uses are limited to conditions such as depression, bulimia nervosa, obsessive-compulsive disorder, and premenstrual dysphoric disorder.

Prozac can also cause side effects, including nausea, sleep changes, fatigue, anxiety, digestive discomfort, sweating, and sexual side effects. Prozac is the brand-name version of the medication, while fluoxetine is its generic name, and both contain the same active ingredient. This medication should only be taken under medical supervision and not for self-directed weight control. For healthy weight loss, guidance from a nutritionist or healthcare professional is recommended.

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