Tribulus terrestris: Benefits, Dosage & Side Effects

Evidence-Based
Manuel Reis
Clinical review: Manuel Reis Registered Nurse OE #79026
Created by: Tua Saude editing team

Tribulus terrestris is a medicinal plant used in traditional medicine and known for its adaptogenic and energizing properties. It contains bioactive compounds such as protodioscin and flavonoids that have antioxidant and anti-inflammatory effects.

Tribulus terrestris is commonly linked to enhanced libido, fertility, and sexual function in both men and women. Research also suggests it may help support muscle growth, regulate blood sugar, promote heart health, and ease menopause symptoms.

Tribulus terrestris is available as both capsules and powder, and the recommended dosage depends on individual factors and specific health goals. Because it may cause side effects or interact with certain medications, it’s important to consult a healthcare professional before using it.

This content is solely for informative purposes and should not replace a medical consultation. Do not interrupt your current treatment without seeking medical guidance.
Tribulus terrestris

Health benefits

The main health benefits of Tribulus terrestris include:

  • Increasing libido in both men and women by enhancing sexual arousal and reducing pain during intercourse, which can promote orgasm;

  • Supporting male sexual performance by promoting blood vessel dilation, improving circulation, and enhancing blood flow to the penis;

  • Relieving menopause symptoms such as hot flashes, irritability, and vaginal dryness;

  • Supporting heart health through its antioxidant and relaxing effects, which can improve circulation and help regulate cholesterol levels;

  • Helping prevent diabetes by enhancing insulin activity and supporting healthy blood sugar control.

In addition, Tribulus terrestris contains protodioscin and protogracillin, which are bioactive compounds that increase DHEA levels in the body and trigger the conversion of testosterone into dihydrotestosterone. This can help to facilitate muscle mass gain.

Recommended dose

Tribulus terrestris is available in both capsule and powder form:

  • Capsules: The recommended dosage depends on factors such as age, sex, overall health, and individual health goals. Generally, the typical dose ranges from 250 to 1,500 mg per day, taken with meals for up to 90 days;
  • Powder: The recommended dose is usually 0.5 to 3 grams per day, divided into up to three doses and taken for a period of up to three months. The powder can be mixed into water, juice, tea, or soup.

Tribulus terrestris may be sold on its own or combined with other botanical supplements, such as Peruvian maca root.

Before starting Tribulus terrestris, consult a healthcare provider or herbal medicine specialist, as the appropriate dosage can vary based on your individual health profile and goals.

Side effects

Some of the most common side effects of Tribulus terrestris include stomach pain, diarrhea, headache, nausea, vomiting, constipation, restlessness, trouble sleeping, or heavier menstrual bleeding.

Long-term or excessive use may lead to hormonal changes, irregular periods, acne, enlarged prostate, or potential kidney and liver damage.

Contraindications for use

Tribulus terrestris is not recommended for children or for people who are pregnant or breastfeeding. It should also be avoided by men with an enlarged prostate, individuals with cardiovascular conditions such as high blood pressure, those with liver disease, or anyone taking lithium.

According to the U.S. Food and Drug Administration (FDA), dietary supplements can change how medications are absorbed or metabolized, which may make a medication too strong or not strong enough, so healthcare providers should be informed about all medicines and supplements being used.

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References
  • FDA. Mixing Medications and Dietary Supplements Can Endanger Your Health. FDA. Updated 06 Feb 2022. Accessed 20 Feb 2026 https://www.fda.gov/consumers/consumer-updates/mixing-medications-and-dietary-supplements-can-endanger-your-health
  • LEISEGANG, Kristina, FINELLI, Renata. Alternative medicine and herbal remedies in the treatment of erectile dysfunction: A systematic review. Arab Journal od Urology. 2021;Vol.19(3.ed):323-339.
  • SOUSA, C, Amanda; LIMA, A, Mizael. Tribulus terrestris Linn como tratamento da sintomatologia da menopausa: uma revisão sistemática. Fitos. 2019;Vol.13(2.ed):195-203.
  • Ștefănescu, Ruxandra; et al. A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties of Tribulus terrestris L. Biomolecules . 2020 May 12;10(5):752. 2020;10(5):1-32.
  • POKRYWKA, Andrzej; et al. Insights into Supplements with Tribulus Terrestris used by Athletes. J Hum Kinet. 2014;41():99–105.
  • ROGERSON, Shane; et al. The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. J Strength Cond Res. 2007;21(2):348-53.
  • SANTOS, Heitor O.; et al. Beyond tribulus (Tribulus terrestris L.): The effects of phytotherapics on testosterone, sperm and prostate parameters. Journal of Ethnopharmacology. 2019;235():392–405.
  • SANTOS, Heitor O.; et al. Beyond tribulus (Tribulus terrestris L.): The effects of phytotherapics on testosterone, sperm and prostate parameters. Journal of Ethnopharmacology. 2019;235():392–405.
  • GamalEl Din, Sameh Fayek. Role of Tribulus terrestris in Male Infertility: Is It Real or Fiction?. Journal of Dietary Supplements. 2017;15(6):1010-1013.
  • ZHU, Wenyi; et al. A review of traditional pharmacological uses, phytochemistry, and pharmacological activities of Tribulus terrestris. Chem Cent J. 2017;11():1-16.