Does Lyrica cause weight gain?

“"I've been taking Lyrica for my nerve pain, but I've noticed I've gained some weight since starting it. Is weight gain a common side effect of Lyrica? What can I do to manage it?"”

Dr. Janessa Oliveira
Biochemist and Pharmacist CRF-SP 22143

Weight gain is a relatively common side effect of pregabalin (Lyrica). One reason for this is an increase in appetite, which can lead to overeating and consuming more calories.

Pregabalin can also contribute to weight gain by causing constipation, which, in some cases, can even result in a bowel obstruction. The risk is higher when pregabalin is used with opioid pain medications like morphine and its derivatives.

To reduce the risk of weight gain while taking pregabalin, it’s important to discuss your concerns with the healthcare provider who prescribed it. They may adjust the dosage, as lower doses typically cause fewer side effects. If the desired effect isn't achieved, they may consider adding other medications with similar effects instead of increasing the pregabalin dose. A healthy diet and regular exercise are also recommended.

Pregabalin is typically prescribed for adults to treat chronic pain, epilepsy, fibromyalgia, or anxiety disorders.

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