Clotrimazole is an antifungal medication used to treat fungal skin infections, such as athlete’s foot, jock itch, and ringworm, as well as vaginal yeast infections. It works by stopping the growth of fungi like Candida albicans, Tinea pedis, Tinea cruris, and Tinea corporis.
This medicine is available as a topical cream, spray, or solution for the skin, and as vaginal creams for yeast infections. It can be found as generic “clotrimazole” or under brand names such as Lotrimin or Gyne-Lotrimin.
Clotrimazole can be purchased over the counter (OTC) at pharmacies and drugstores. It should be used as directed by the product label or by a healthcare provider such as a gynecologist, dermatologist, or primary care provider.
Indications for use
Clotrimazole is approved for the treatment of:
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Athlete’s foot (Tinea pedis);
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Jock itch (Tinea cruris);
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Ringworm (Tinea corporis);
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Vaginal yeast infections (Vulvovaginal candidiasis).
Clotrimazole should always be used following medical guidance or the directions on the package to ensure the correct dose and treatment duration.
Dosing instructions
Clotrimazole is for external use only and should be applied to the affected skin or used in the vaginal area, depending on the formulation. The main forms include:
1. Clotrimazole topical cream (1%)
Topical clotrimazole cream is indicated for athlete’s foot, jock itch, and ringworm.
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How to use: Apply a thin layer to the affected area and surrounding skin twice daily (morning and evening);
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Duration: Continue use for 2 weeks for jock itch or 4 weeks for athlete’s foot and ringworm, even if symptoms improve earlier.
Before applying, wash and dry the affected area thoroughly. Clothing, socks, and towels that come into contact with the area should be changed daily to prevent reinfection.
2. Clotrimazole topical solution or spray (1%)
Clotrimazole solution or spray is used for the same fungal skin infections as the cream.
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How to use: Apply enough solution to cover the affected area twice daily, as directed by a healthcare provider or the instructions on the label;
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Duration: Use for 2 to 4 weeks, depending on the infection type and clinical response.
Before each application, clean and dry the affected skin thoroughly.
3. Clotrimazole vaginal cream (1%)
Clotrimazole vaginal cream is indicated for vaginal yeast infections caused by Candida albicans.
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How to use: Insert the cream deep into the vagina once daily at bedtime, using the applicator provided;
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Duration: Use for 7 consecutive days, or as advised by a healthcare provider.
During treatment, avoid tampons, douching, or vaginal spermicides. Refrain from sexual intercourse, as the cream may reduce the effectiveness of condoms and diaphragms.
Side effects
Common side effects of clotrimazole include:
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Mild burning, redness, or irritation at the application site;
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Itching or peeling of the skin;
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Abdominal discomfort (vaginal formulations).
Serious allergic reactions are rare but can occur. Seek medical attention if you experience difficulty breathing, swelling of the lips, tongue, or face, or severe itching or hives.
If symptoms worsen or persist after the recommended course, consult a healthcare provider.
Contraindications for use
Clotrimazole should not be used by anyone allergic to this medication or any of its ingredients.
Although topical use is generally considered safe, people who are pregnant or breastfeeding should consult a healthcare provider before use. Vaginal clotrimazole products may be used during pregnancy only under medical supervision.
Clotrimazole products are for external use only. Avoid contact with eyes, mouth, or mucous membranes, other than the vaginal mucosa as directed.
Because clotrimazole cream can weaken latex, avoid relying solely on condoms, diaphragms, or vaginal spermicides during treatment.