Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and stiffness caused by osteoarthritis or rheumatoid arthritis. This medication may also be prescribed by a healthcare provider to treat other types of moderate to severe pain in adults.
This drug is sometimes used for the treatment of juvenile rheumatoid arthritis in children who are over 16 years of age. It is important to only administer this medication to children under the direct supervision and guidance of a pediatrician.
Meloxicam is available at most pharmacies and drugstores with a valid medical prescription as a generic or under the brand name Mobic. It is typically sold in tablet form or as an injectable solution and must be used exactly as directed by your doctor.
What it is used for
In the United States, the FDA officially approves meloxicam for the relief of signs and symptoms of the following conditions:
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Osteoarthritis
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Rheumatoid arthritis
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Juvenile rheumatoid arthritis (in children 2 years of age and older)
Additionally, a doctor may prescribe meloxicam off-label for other conditions common in clinical practice, such as ankylosing spondylitis, trauma or physical injury, muscle strains and menstrual cramps.
Is meloxicam a corticosteroid?
Meloxicam is not a corticosteroid and does not contain any steroid components in its formulation.
This medication belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the body's production of inflammatory substances, such as prostaglandins, which helps manage moderate to severe pain.
How to use
Meloxicam is intended for use in adults and children 2 years of age or older depending on the condition. The specific dosage and administration method vary based on the condition being treated and the form of the medication:
1. Meloxicam tablets
Meloxicam tablets are available in 7.5 mg and 15 mg strengths. Typical adult and pediatric dosages include:
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Osteoarthritis: The standard recommended dose for adults is 7.5 mg per day (one 7.5 mg tablet or half of a 15 mg tablet). If symptoms do not improve, a doctor may increase the dose to a maximum of 15 mg per day.
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Rheumatoid arthritis: The standard recommended dose for adults is 15 mg per day (two 7.5 mg tablets or one 15 mg tablet). Depending on the patient's response, a doctor may reduce the dose to 7.5 mg per day.
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Juvenile rheumatoid arthritis: For children 2 years and older who weigh at least 60 kg (approximately 132 lbs), the recommended dose is 7.5 mg once daily. For children weighing less, a doctor will determine the dose based on weight.
The maximum daily dose for any condition is 15 mg. For elderly patients, individuals with renal insufficiency, or those undergoing hemodialysis, the maximum daily dose is 7.5 mg.
Meloxicam should be taken as a single daily dose at the same time each day. The tablet should be swallowed with a full glass of water during a meal.
2. Meloxicam injectable solution
In the United States, the FDA approved injectable form of meloxicam (such as Anjeso) is typically administered as a 30 mg dose once daily. This form is used in a clinical or hospital setting for the management of moderate to severe pain. It is delivered directly into a vein by a healthcare professional.
Possible side effects
The most common side effects associated with meloxicam include heartburn, stomach upset, nausea, vomiting, abdominal pain, constipation, gas, or diarrhea.
Other potential side effects include esophagitis, stomach or intestinal ulcers, gastrointestinal bleeding, anemia, changes in blood cell counts, skin blistering, itching, hives, increased light sensitivity, or mouth sores (stomatitis).
In rare cases, meloxicam may cause serious conditions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute asthma attacks, or vertigo. It may also lead to ringing in the ears, dizziness, high blood pressure, palpitations, abnormal kidney function (elevated creatinine or urea), acute kidney failure, and severe allergic reactions, including anaphylaxis.
Does meloxicam cause drowsiness?
Drowsiness is a possible side effect of meloxicam, along with other central nervous system effects such as dizziness, vertigo, or blurred vision.
Because of these risks, patients should use caution or avoid activities like driving or operating heavy machinery while taking this medication. Alcohol should be avoided, as it can worsen drowsiness and dizziness.
Who should not take it
Meloxicam should not be used by children or adolescents under 16 years of age, or by women who are pregnant or breastfeeding.
This medication is contraindicated for individuals with active stomach ulcers, gastrointestinal bleeding, ulcerative colitis, Crohn’s disease, or blood clotting disorders. It should also be avoided by those with severe heart, kidney, or liver failure, or those who experience asthma, rhinitis, nasal polyps, or hives triggered by aspirin.
Furthermore, meloxicam should not be taken by anyone with a known allergy to meloxicam or other NSAIDs like aspirin, ibuprofen, or naproxen. Patients with lactose intolerance should use caution, as the tablet formulation contains lactose.
Meloxicam may interact with other medications, potentially reducing their effectiveness or increasing risks. These include amlodipine, anesthetics, other NSAIDs (such as indomethacin), beta-blockers, estrogens, anticoagulants, anticonvulsants, lithium, and sympathomimetics. Always consult a doctor before starting treatment.