Libido-Boosting Supplements for Females: Medications & Natural Remedies

Libido-boosting supplements for females include flibanserin, bremelanotide, testosterone, and DHEA, as well as natural options such as Tribulus terrestris, maca root, ginseng, and Ginkgo biloba.

A woman’s libido can decrease due to hormonal changes, the use of estrogen-containing medications, menopause, or hypoactive sexual desire disorder (HSDD), which is characterized by a reduced or absent sexual desire lasting at least six months without an identifiable cause.

Treatment with medications or supplements should always be guided by a gynecologist after evaluating hormone levels. Maintaining a healthy diet, getting adequate sleep, and exercising regularly can also help naturally improve libido.

Main treatments

The most common libido-boosting supplements and medications for women include:

1. Flibanserin

Flibanserin is an FDA-approved medication used to treat hypoactive sexual desire disorder in premenopausal women. This condition involves a persistent lack of sexual desire for at least six months without any apparent cause.

Often called the “female Viagra,” flibanserin works by regulating levels of brain neurotransmitters, such as serotonin and dopamine, which play a role in sexual desire and satisfaction.

Treatment should be prescribed by a gynecologist after evaluating overall health, and the typical dose is one tablet daily at bedtime.

Flibanserin should not be used by women who are pregnant or breastfeeding, have liver problems, or are allergic to its components. It should also not be combined with alcohol or certain medications, as this may increase the risk of side effects.

2. Bremelanotide

Bremelanotide (brand name Vyleesi) is another FDA-approved treatment for premenopausal women with hypoactive sexual desire disorder. It is a melanocortin receptor agonist that helps increase sexual desire by activating specific pathways in the brain.

Bremelanotide is used on demand as a self-injection under the skin of the abdomen or thigh, about 45 minutes before anticipated sexual activity. The maximum recommended frequency is one dose every 24 hours and no more than eight doses per month.

Common side effects include nausea, flushing, and injection site reactions. It should not be used by women with uncontrolled high blood pressure or heart disease.

3. Testosterone

Testosterone is a hormone that may be prescribed off-label by a gynecologist or endocrinologist for women with hypoactive sexual desire disorder after other causes have been ruled out.

Low testosterone levels in women can occur due to aging, surgical removal of the ovaries, or the use of estrogen-based medications. These changes can cause reduced libido and vaginal dryness. Read more about low testosterone in women.

When used for libido, only low-dose transdermal testosterone (gels or creams) is recommended, under close medical supervision. Oral and injectable forms are not recommended due to safety concerns. A healthcare provider should monitor hormone levels and possible side effects during treatment.

Possible adverse effects include acne, hair loss, and voice deepening.

4. DHEA

Dehydroepiandrosterone (DHEA) is one of the body’s most abundant hormones, and supplementation may be recommended when levels are low, especially during menopause.

DHEA supplements can act as a natural form of hormone replacement to help improve libido, reduce vaginal dryness, and boost energy levels.

However, DHEA should only be used under the supervision of an endocrinologist after hormone testing. It is not recommended for women with a history of breast or ovarian cancer, or those taking medications such as tamoxifen, anastrozole, or letrozole, as it may interfere with their effects.

5. Tribulus terrestris

Tribulus terrestris is a medicinal plant with aphrodisiac properties that may help boost libido in women. It can also help relieve menopausal symptoms such as vaginal dryness and irritability.

It is available as a powder (0.5 to 3 g per day) or in capsules (250 to 1500 mg daily). The correct dosage should be determined by a doctor or licensed herbalist based on age, health condition, and desired results.

6. Maca root

Maca root (Lepidium meyenii) is a natural supplement that may help increase libido due to its tonic and mood-enhancing effects. It can also reduce fatigue and increase energy.

The recommended dose of maca root capsules is around 3 g per day, divided into three doses. Maca powder can also be added to smoothies, yogurts, or fruit juices, using 2 to 3 teaspoons daily.

Although maca root is considered safe, more research is needed to confirm its benefits for libido. It should only be used under the supervision of a healthcare professional.

7. Ginseng

Ginseng is a medicinal plant that acts on the nervous system by stimulating the production of dopamine, a neurotransmitter associated with pleasure and sexual desire.

It is commonly used to improve sexual performance and increase libido in women. The usual recommended dose is 1 to 3 capsules daily, as advised by a doctor, registered dietitian, or herbalist.

Ginseng should not be taken by people using antidepressants or diabetes medications, or those with heart disease or asthma.

8. Ginkgo biloba

Ginkgo biloba may help improve female libido by increasing blood flow to the genital area and balancing neurotransmitters like dopamine and serotonin, which affect mood and sexual pleasure.

The recommended dose is typically between 40 and 120 mg, taken three times daily with meals to improve absorption.

Although Ginkgo biloba is generally considered safe, it should be used under medical supervision. It is not recommended during pregnancy or breastfeeding, or for people with bleeding disorders.