Keloid treatment ointments, such as Kelo-cote, Mederma, and ScarAway, are used to treat or prevent thick scars and keloids. These products contain ingredients that help hydrate, protect, and repair the skin, speeding up regeneration and improving the healing process.
A keloid is a raised scar that forms due to excessive collagen production during healing. It can develop after ear or nose piercings, surgeries, tattoos, acne, or skin injuries.
These ointments should be used under the guidance of a dermatologist, as they may cause side effects like redness, burning, or swelling. In some cases, the doctor may also recommend other keloid treatments, such as corticosteroid injections, laser therapy, radiation therapy, or surgery.
7 ointments for keloid treatment
The following are some of the best FDA-cleared and widely available ointments to help reduce keloids:
1. Mederma Advanced Scar Gel
Mederma Advanced Scar Gel is widely used for the treatment and prevention of scars and keloids caused by surgeries, burns, piercings, or injuries. It has anti-inflammatory and skin-repairing properties that help soften and improve the appearance of scars.
Its formula contains cepalin (onion bulb extract), which has been shown to reduce scar formation, improve skin hydration, and support collagen remodeling.
How to use:
Apply a thin layer of Mederma to the scar or keloid once daily, gently massaging until fully absorbed. For recent scars, begin treatment once the wound is fully closed and stitches have been removed. For older scars or keloids, consistent daily use is recommended for at least 8 weeks.
2. Kelo-cote
Kelo-cote is a transparent silicone gel containing polysiloxanes and silicon dioxide. It hydrates the skin and forms a protective barrier, supporting healing and helping to prevent keloid formation.
It is suitable for scars from surgeries, C-sections, burns, and injuries. It should only be used on closed wounds after the removal of stitches.
How to use:
Clean the area with water and mild soap and dry thoroughly. Apply a thin layer of Kelo-cote without massaging, and allow it to dry for 4 to 5 minutes before dressing or applying other products.
Apply twice a day to keep continuous contact with the skin for 24 hours. Treatment should last for at least 2 months or as advised by a dermatologist.
3. ScarAway Silicone Scar Gel
ScarAway Silicone Scar Gel is an FDA-cleared treatment that helps flatten, soften, and fade both old and new scars and keloids. It forms a breathable silicone layer over the skin, supporting moisture retention and collagen regulation.
It is commonly used after surgeries, burns, or traumatic skin injuries.
How to use:
Clean and dry the affected area, then apply a thin layer of gel twice daily. Allow it to dry completely before applying clothing or other products. Consistent use for at least 60 days is recommended for best results.
4. Cicatricure gel
Cicatricure gel contains botanical extracts such as walnut leaf, aloe vera, chamomile, marine thyme, onion extract, and bergamot oil. Although marketed primarily for cosmetic use, it helps hydrate and regenerate the skin, improving the appearance, texture, and color of keloids or thick scars.
It should only be applied to fully healed skin and is not recommended during pregnancy or breastfeeding.
How to use:
Clean the area with water and mild soap and dry completely. For old scars or keloids, apply a generous amount of Cicatricure gel three times daily for 3 to 6 months.
Recent scars should only be treated under the supervision of a dermatologist.
5. Celacyn Hydrogel
Celacyn Hydrogel is a medical-grade product containing hypochlorous acid and silicone, offering anti-inflammatory and antibacterial benefits. It hydrates and protects the skin, speeding up recovery and improving skin texture and appearance.
It is used for thick scars and keloids resulting from surgery, burns, or trauma. It should not be applied to third-degree burns or open wounds.
How to use:
Wash the area with water and a mild soap, and dry completely. Apply a thin layer of the gel 2 to 3 times per day, or as directed by a healthcare provider.
6. BioCorneum
BioCorneum is an FDA-cleared silicone gel that includes SPF 30. It helps protect scars from UV exposure while reducing redness, discoloration, and raised texture. It is especially useful for exposed areas like the face, chest, or arms.
This gel is used to prevent and treat keloids and hypertrophic scars from surgeries, cosmetic procedures, or burns.
How to use:
Apply a thin layer twice a day to clean, dry skin. Allow the gel to dry before sun exposure, dressing, or using other products. Use consistently for at least 2 months.
7. Silagen Scar Gel
Silagen Scar Gel is a medical-grade silicone product sold through dermatologists and plastic surgeons. It improves elasticity and smoothness while reducing redness and itchiness associated with keloids and surgical scars.
It is recommended for use after procedures such as C-sections, orthopedic surgeries, or cosmetic treatments.
How to use:
Apply to healed skin twice a day for 8 to 12 weeks, or longer depending on scar maturity. Wait for the gel to dry before applying sunscreen, makeup, or clothing.
When not to use
Most keloid ointments are sold over the counter and can be used without a prescription. However, individuals who are pregnant or breastfeeding, have a history of allergies or sensitive skin, or are treating children should consult a healthcare provider before use.
When to see a doctor
A dermatologist should evaluate the keloid and recommend the most appropriate ointment or other treatment, especially if the keloid causes pain, discomfort, or cosmetic concerns.
How to prevent keloids while healing
To prevent keloid formation, it's important to take steps such as using sunscreen daily, avoiding sun exposure on healing areas, and applying dermatologist-recommended ointments only once the skin has fully healed.
A balanced diet rich in healing-supportive foods—such as lean meats, eggs, fish, oranges, strawberries, or Brazil nuts—may also help. These foods support tissue regeneration and can reduce the appearance of scars.