Fluticasone and salmeterol is a combination medication used to manage asthma and chronic obstructive pulmonary disease (COPD). It is administered by oral inhalation.
Salmeterol is a long-acting bronchodilator that helps keep the airways open, while fluticasone is a corticosteroid that reduces inflammation in the lungs.
In the United States, this medication is available under brand names such as Advair Diskus, Advair HFA, and AirDuo RespiClick, all of which are FDA-approved and require a prescription.
What it is used for
Fluticasone and salmeterol is used to:
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Control asthma
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Treat chronic obstructive pulmonary disease (COPD)
This combination helps prevent and manage symptoms like shortness of breath, wheezing, coughing, and chest tightness. In people with COPD, including emphysema and chronic bronchitis, it helps reduce the number of flare-ups when symptoms worsen, decreasing the need for additional medications and improving quality of life.
While fluticasone and salmeterol helps control symptoms of respiratory diseases, it does not cure them.
Fluticasone and salmeterol dosage
The dosage of fluticasone and salmeterol varies depending on age and the type of inhaler used, as shown in the table below:
It is important to use only the dose prescribed by a doctor to ensure safe and effective treatment, minimize side effects, and achieve optimal control of respiratory symptoms.
How to take fluticasone and salmeterol
Fluticasone and salmeterol is taken by inhalation using a device that delivers the medication in powder or aerosol form. It should be used while sitting or standing upright.
For children or people who have difficulty using inhalers properly, a spacer device may be recommended to help ensure that the medication reaches the lungs effectively.
How to use the inhaler
Fluticasone and salmeterol should be used while sitting or standing upright. Before inhaling, exhale completely. Place the mouthpiece in your mouth, start to inhale slowly, and press the inhaler to release the medication.
After inhaling, hold your breath for as long as possible to allow proper absorption of the medicine.
To reduce throat irritation, prevent oral thrush (oropharyngeal candidiasis), and minimize other local side effects, rinse your mouth thoroughly and wash your hands after each use.
Possible side effects
The most common side effects of fluticasone and salmeterol include:
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Runny nose and sneezing
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Sore or irritated throat
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Headache or dizziness
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Muscle weakness or pain
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Nausea, vomiting, or diarrhea
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Trouble sleeping
Other temporary effects, such as tremors, palpitations, or muscle cramps, may appear early in treatment and usually improve as the body adjusts to the medication.
If any unusual or persistent symptoms occur, it’s important to contact the prescribing doctor to ensure the medication is working properly and make adjustments if needed.
Contraindications for use
Fluticasone and salmeterol should not be used by people who are allergic to either ingredient or to any of the components in the medication, including milk proteins.
People with heart disease, diabetes, or high blood pressure should inform their doctor before using this medication, as it can increase blood sugar levels and heart rate.
This medication is not recommended for children under 4 years of age or for breastfeeding mothers. During pregnancy, it should only be used if the potential benefits outweigh the risks, as determined by a doctor. Treatment should never be stopped without medical advice.