Spironolactone for acne may be prescribed by some healthcare providers, even though it’s not specifically approved for that purpose. It’s most often recommended for women with higher levels of androgens (male hormones).
In general, spironolactone is considered safe and is usually well tolerated. However, spironolactone should not be used by people with kidney problems, high potassium levels on a blood test, an allergy to spironolactone, or those who take the medication eplerenone.
Still, you shouldn’t take spironolactone for acne without guidance from a healthcare provider. A dermatologist or endocrinologist can help determine the best treatment plan for you, which may or may not include spironolactone.