Yes, Lexapro can make you tired. Escitalopram (Lexapro) can cause drowsiness in some people, especially early on. The opposite effect can also happen, but sleepiness is considered a common side effect, particularly during the first few weeks of treatment.
Other common side effects of Lexapro include headache, nausea, changes in appetite, low libido, diarrhea, or feeling tired. These effects are more common when you first start treatment but usually decrease over time if you take the medication as directed by the prescribing provider.
The antidepressant effects of escitalopram oxalate 10 mg may take about 2 to 4 weeks to become noticeable. If you have unwanted side effects, such as tiredness or fatigue, the best step is to talk with a psychiatrist or the healthcare provider who prescribed Lexapro to see whether your treatment needs an adjustment.