Estradiol can cause weight changes in some people. It may also cause fluid retention and swelling, which can make your weight go up temporarily.
Estradiol is available in several forms, including tablets, skin patches, and gels. Side effects can vary depending on the product and may include headaches, breast pain or tenderness, bloating, nausea, and mood changes.
Estradiol is commonly used to treat menopause symptoms such as hot flashes and vaginal dryness. Certain estrogen products may also be prescribed to help prevent bone loss after menopause.
If you have questions about estradiol or its side effects, talk to your gynecologist or primary care provider.