Does sertraline cause weight gain?

Daisy Oliveira
Registered Nurse CNO #13564387

Sertraline can cause weight gain in some people, but the change is usually small and does not happen to everyone. In some cases, it can also change appetite in the opposite direction, which means some people may notice less hunger instead of more. 

Weight changes with sertraline tend to vary over time and from person to person. Some people may not notice any change, while others may slowly gain weight after using it for a longer period. Appetite, eating habits, activity level, sleep, and the condition being treated can all play a role.

Sertraline should not be used for weight loss, and it should not be stopped suddenly without medical advice. If weight gain becomes noticeable or bothersome, the safest step is to speak with the prescribing doctor so the treatment can be reviewed and adjusted.

A psychiatrist is usually the most appropriate specialist to review this medication, although a primary care provider can also help. Any dose change or switch to another medicine should only be done with medical guidance.

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