How to Remove Lice from Hair: Medications & Natural Remedies

Evidence-Based

Head lice are small insects that attach to the scalp and hair, feeding on blood and causing itching and discomfort. Understanding how to remove lice from hair permanently involves combining proven medical treatments with practical cleaning strategies.

Effective options include medicated shampoos, prescription lotions, home remedies, and fine-tooth combing. These methods target both adult lice and their eggs, reducing the risk of reinfestation.

Most cases can be managed at home with consistent treatment and prevention steps, but severe or resistant infestations may require medical attention. Doctors may recommend alternative medications or further evaluation if lice persist, as untreated cases can lead to ongoing scalp irritation and secondary skin infections.

This content is solely for informative purposes and should not replace a medical consultation. Do not interrupt your current treatment without seeking medical guidance.
Mother combing child's hair, looking for lice and nits

Medicated treatments

When considering how to remove lice from hair permanently, medicated treatments help ensure better results and reduce the risk of recurrence. These options can be used alone or together with combing, and some may require a second application based on product instructions.

1. Over-the-counter options

Medications you can purchase at the pharmacy without a prescription include:

  • Permethrin 1% cream rinse: Apply to washed, towel-dried hair and rinse after the label-directed time. Check for live lice and repeat in 7 to 9 days if needed.
  • Pyrethrins with piperonyl butoxide: Apply to dry hair and rinse after the instructed time. A second application after 7 to 9 days is often recommended.

Speak to the pharmacist about where to find them and how to use specific products. 

2. Prescription options

Medications that require a prescription to purchase include:

  • Ivermectin 0.5% lotion: Single-application option for individuals 6 months and older.
  • Spinosad 0.9% suspension: Ovicidal treatment for individuals 4 years and older; nit combing may be optional.
  • Malathion 0.5% lotion: Ovicidal, may be preferred where resistance is suspected; use with care and keep away from heat sources.
  • Benzyl alcohol 5% lotion: Kills live lice but not nits, so a second application is usually needed.

Use products exactly as labeled for age and safety, and combine with careful nit removal to improve outcomes. If live lice are seen after following directions, speak with a healthcare provider about switching to a different class of treatment.

Home remedies

Natural methods can support treatment, especially alongside combing, but results are variable and formulations are not standardized. For safety, essential oils should be used with caution in children and avoided near the eyes, and any skin irritation should be a reason to stop.

1. Wash your hair with vinegar

The first step is to wash your hair with a mixture of vinegar and warm water. Vinegar contains properties that kill and get rid of nits and lice. This mixture should be applied directly to the whole scalp.

Ingredients

Preparation method

Mix 1 cup of vinegar with 1 cup of warm water. Next, distribute this mixture onto the scalp and cover your hair with a hair cap. Let this sit for approximately 30 minutes. Then, wash your hair normally with your usual shampoo.

Evidence for vinegar is mixed. It may help loosen nits for combing, but it is less reliable than approved medicated treatments.

2. Use an essential oil mixture

The second step is to apply a mixture of essential oils directly on your scalp and hair, put a hair cap on and leave the mixture to work for 20 minutes.

Ingredients

  • 50 mL of coconut oil;
  • 2 to 3 drops of essential tea-tree oil;
  • 2 to 3 drops of ylang ylang essential oil;
  • 50 mL of apple cider vinegar.

Preparation method
Mix all the ingredients together and apply directly on hair. Leave it in for 20 minutes and then wash it out with your usual shampoo.

Studies on essential oils show variable results. If used, they should complement, not replace, proven treatments and careful combing.

3. Comb your hair using a fine-tooth comb

The third step is to run a fine-tooth comb through your whole hair, going through each section carefully in order to make sure that every part of your hair gets thoroughly visualized and combed.

Instead of using a fine-tooth comb, you can also use an electric lice comb on dry hair, which is even more efficient in detecting and eliminating lice. This comb makes a continuous sound while it is turned on and a more intense and higher-pitched sound when it detects a louse. The electric comb emits an ultrasound frequency that is not sensed by the person but is lethal to lice.

Daily or frequent combing for 10 to 14 days improves removal. Consistency and technique are key for best results.

These methods can help, but adding an approved medicated option and consistent nit removal generally leads to higher success rates.

Cleaning & prevention steps

Simple cleaning steps lower the chance of getting lice again and support long-term control. Focus on items that had direct head contact in the 48 hours before treatment.

1. Wash your clothes in hot water

Lice can be transmitted through brushes, combs, hats, pillow-cases or bed sheets. Therefore, it is very important to wash these objects frequently, to avoid a new infestation or transmission of the parasite to another person.

All objects that have been in contact with affected scalps (such as bed sheets, blankets, clothes, soft toys, hair bands and ties, hats, caps, carpets, pillow cases and sofa covers) need to be washed in hot water at a temperature over 140°F or 60°C in order to kill the lice.

Dry items on high heat for 20 to 40 minutes when possible. Items that cannot be washed can be sealed in a plastic bag for up to two weeks or placed in a hot dryer if safe for the fabric.

2. Disinfect personal items

Soak combs and brushes in hot water of about 130°F (54°C) for 5 to 10 minutes. Avoid sharing hats, headphones, hair accessories and towels.

3. Reduce spread and reinfestation

Teach children to avoid head-to-head contact during play and sports. Tie long hair in braids or buns in group settings. Check close contacts and treat confirmed cases at the same time.

4. Repeat all steps after 9 days

Lice have a life cycle of 9 days and, therefore, nits that were not removed in the first treatment can end up developing into lice within this time frame. Therefore, nine days after the first treatment we recommend you repeat all the steps. This will ensure that all lice are eliminated.

After repeating treatment and combing, recheck the scalp and continue routine inspections for several days to confirm there are no live lice.