Sneezing can feel good because it suddenly relieves the uncomfortable tickle or urge that builds up inside the nose. The sneeze reflex also helps clear irritants, mucus, or allergens from the upper airway, so the feeling afterward may be one of relief or satisfaction.
A sneeze starts when chemical or mechanical irritation activates sensory nerves in the nose. These signals travel through pathways involving the trigeminal nerve and brainstem, triggering a coordinated reflex that includes a deep breath, pressure buildup, and a forceful burst of air.
Sneezing is especially common with allergic rhinitis. Allergens can trigger inflammation and the release of histamine, which stimulates nasal sensory nerves and causes itching and repeated sneezing. Once the sneeze occurs, removing some of that irritating material may reduce the sensation that triggered the reflex.
There is not enough evidence to say that sneezing feels pleasurable because it releases endorphins or dopamine. Intentionally blocking a sneeze by closing the nose and mouth can create very high pressure and has been linked to rare injuries, so sneezes should not be forcefully suppressed.