What are polymorphonuclear leukocytes?

“My blood test showed something called polymorphonuclear leukocytes, and the doctor said the level was a bit off. I’m not sure what that means. Should I be worried, or could it just be a sign of an infection?”

Dr. Janessa Oliveira
Biochemist and Pharmacist CRF-SP 22143

Polymorphonuclear leukocytes are a type of white blood cell named for their multi-lobed nucleus. Also called granulocytes, this group includes neutrophils, eosinophils, and basophils, with neutrophils being the most common type found in the bloodstream.

These cells are essential for the body’s immune defense, helping identify and destroy bacteria, viruses, and other harmful agents. Having normal levels of polymorphonuclear leukocytes in a blood test usually indicates that the immune system is functioning properly.

If test results show higher or lower levels of polymorphonuclear leukocytes than normal, it may suggest an infection, inflammation, allergic reaction, or another condition that affects the immune system.

It’s important to discuss any abnormal results with a doctor, preferably a hematologist, a primary care physician, or the healthcare provider who ordered the test, to determine the cause and whether further evaluation is needed.

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