Shoulder blade pain is usually not a sign of cancer. In most people it comes from muscles, joints, or posture, like spending long hours at a computer, lifting something awkwardly, or sleeping in an odd position. Cancer is considered more likely when the pain is persistent, keeps getting worse over time, or appears together with other warning signs such as unexplained weight loss, tiredness, or breathing changes.
Cancer can cause shoulder blade pain in a few situations, such as tumors in the top of the lung, liver or gallbladder disease, or cancer that has spread to the bones. In these cases, pain often does not improve with rest or regular pain medicine and may be stronger at night.
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Anyone with shoulder blade pain that lasts for several weeks, keeps waking them up at night, or happens in someone who has had cancer before should be evaluated by a doctor. A family doctor or general practitioner can examine the shoulder and back, order tests if needed, and refer to an orthopedist, pulmonologist, or oncologist if a serious cause is suspected.