Alendronate is a medication prescribed to treat osteoporosis in men and postmenopausal women. It helps lower the risk of fractures in the spine and hip.
This drug works by slowing down bone resorption, which helps preserve bone density and reduces the chance of fractures. It is available in tablets containing 70 mg of alendronate, taken at least 30 minutes before breakfast.
Alendronate can be found in pharmacies under brand names such as Fosamax, or as a generic version. In some countries, it may also be available through public health programs when prescribed by a doctor.
What alendronate is used for
Alendronate is indicated for the treatment of osteoporosis, a condition in which bone density decreases, increasing the risk of fractures in the spine or hip in men and postmenopausal women.
This medication should be prescribed by an orthopedic specialist after diagnostic testing. The duration of treatment should always follow medical guidance.
How to take alendronate
Alendronate tablets should be taken by mouth with a full glass of water on an empty stomach, at least 30 minutes before breakfast. It is important to remain upright and avoid lying down after taking the tablet to prevent irritation of the esophagus.
The recommended dose for men and postmenopausal women is one 70 mg alendronate tablet once a week, for the length of treatment prescribed by the doctor.
Possible side effects
The most common side effects of alendronate include constipation, diarrhea, abdominal pain, heartburn, stomach discomfort, nausea, and pain in the bones or joints.
In some cases, more serious side effects may occur and require immediate medical attention. These include difficulty or pain when swallowing, chest pain, coughing up blood, pain in the ribs, thigh, or hip, muscle spasms or contractions, or tingling in the hands, feet, or mouth.
Alendronate may also cause allergic or anaphylactic reactions. Emergency care should be sought right away if symptoms such as swelling of the mouth, tongue, or face, or difficulty breathing occur.
Who should not use alendronate
Alendronate should not be used by children, adolescents, pregnant or breastfeeding women, or people with narrowing of the esophagus, conditions that prevent remaining upright for at least 30 minutes, or certain esophageal disorders.
This medication should also not be taken by anyone allergic to alendronate or any of the ingredients in the tablet.
In addition, alendronate is not recommended for people with vitamin D deficiency, severe kidney failure, or low calcium levels in the blood.