Simethicone is an over-the-counter (OTC) anti-gas medicine used to relieve bloating, abdominal pressure, and fullness caused by excess gas in the stomach or intestines. It works by breaking down gas bubbles, making them easier to eliminate and helping to ease discomfort.
This medication is available in pharmacies as oral drops, chewable tablets, or softgel capsules, and is safe for adults, children, and infants when used as directed. Simethicone is not absorbed by the body, which means it acts only in the digestive tract and is generally well tolerated.
Although simethicone is safe for most people, medical advice is recommended if symptoms persist or worsen. A doctor may investigate other causes of gas, such as food intolerances or gastrointestinal conditions, and recommend treatment adjustments if needed.
What it's used for
Simethicone is used for the relief of symptoms like:
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Abdominal discomfort and cramping
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Frequent burping
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Excessive gas
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Excessive stomach noises
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Abdominal bloating
Simethicone relieves pressure, bloating, and fullness (gas). A healthcare provider may also recommend its use before certain exams, such as an endoscopy or colonoscopy, to help reduce gas bubbles in the digestive tract and improve visualization.
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The way to use simethicone varies according to the presentation and includes:
1. Simethicone drops 20 mg/0.3 mL
Simethicone drops can be used by adults, babies, and children. Dosing varies depending on age:
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Infants under 2 years old: 20 mg (0.3 mL) orally after meals and at bedtime, as needed, up to 12 doses per day (maximum 240 mg/day); always follow pediatrician advice.
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Children 2 to 12 years old: 40 mg (0.6 mL) orally after meals and at bedtime, as needed, up to 12 doses per day (maximum 480 mg/day).
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Adults and children over 12 years old: Follow adult dosing guidelines.
When administering simethicone to a baby or young child, the drops can be mixed with water, baby formula, or other liquids to facilitate swallowing. The bottle should be shaken before each use.
2. Simethicone 80 mg chewable tablets
Simethicone in 80 mg chewable tablets is indicated for adults and children over 12 years. The usual dose is 1 to 2 tablets after meals and at bedtime. The maximum daily dose should not exceed 6 tablets (480 mg/day), unless advised by a doctor.
3. Simethicone 125 mg softgel capsules
Simethicone in 125 mg softgel capsules is recommended for adults. The usual dose is one capsule after meals and at bedtime, up to four times daily. The maximum daily dose is 500 mg.
Possible side effects
Simethicone is generally well tolerated because it is not absorbed by the body. It acts only on the gases present in the stomach or gut and is completely eliminated through the stool.
However, some side effects that may occur with simethicone use include hives, itching, swelling, and skin redness.
Simethicone can cause an allergic reaction that requires immediate medical attention. Therefore, if symptoms like difficulty breathing, coughing, chest pain, swollen throat, hives, or swelling in the mouth, tongue, or face occur, stop treatment immediately and proceed to the nearest emergency room.
Contraindications and precautions
Simethicone should not be used by anyone who is allergic to simethicone or any of its components.
It is considered safe during pregnancy and breastfeeding because it is not absorbed by the body and does not pass into breast milk, but its use should always be guided by a healthcare professional when gas or bloating causes discomfort.
Some chewable tablets may contain phenylalanine (aspartame), so people with phenylketonuria (PKU) should check the label before use; this warning does not apply to dye-free infant drops.
The medicine should be kept out of reach of children, and medical advice should be sought if symptoms persist or worsen.